The interdisciplinary research team headed by Professors Seyun Kim, Gwangrog Lee, and Won-Ki Cho from the Department of Biological Sciences revealed crucial mechanisms regulating gene expression in animal cells on January 22, according to KAIST.
Cancer
Data from this 28-country multi-institutional effort helped the Food and Drug Administration (FDA) approve this combination more quickly in December 2024, giving patients with BRAF V600E-mutant mCRC a new and effective first-line treatment choice.
In order to build the groundwork for creating CAR molecules that optimize antitumor activity beyond B cell malignancies, researchers set out to comprehend how CAR T cells with various signaling domains function at the molecular and cellular levels.
Scientists created new medications to suppress PD-1 and activate the body’s immune system to combat cancer after its discovery.
According to the study, when a cell spreads out over a rigid surface, the nuclear lamina, which serves as a scaffold to help the nucleus maintain its form and structure, becomes taut and unwrinkled.
Researchers controlled inflammation from multiple sclerosis in mice by programming immune cells to target glioblastoma. There will soon be a clinical trial to test the glioblastoma technique.
The treatment of numerous severe illnesses, including cancer, may improve as a result of a recently published study headed by Wayne State University on a novel understanding of chronic inflammation. Their findings were published in the journal Frontiers in Immunology. According to Dr. Maddipati’s research, acute inflammation which is caused […]
T cells gradually lose their effectiveness when exposed to tumors repeatedly because they express coinhibitory receptors, which function as brakes.
Teri Boudreaux is thankful for the time she gets to spend with her family, whether it’s hiking, playing with her grandkids, travelling with her spouse, lounging on the beach, or taking up new interests like pickleball. She has survived breast cancer twice. In spite of everything, though, she still harbours […]
However, it’s also known that TET2 mutations can result in conditions other than cancer. A portion of persons over the age of 70 also had TET2 mutations, which raise the risk of diabetes, heart disease, stroke, and other inflammatory diseases as well as CHIP.